منابع مشابه
Feast or famine
Lysosomal storage diseases are metabolic disorders characterized by the accumulation of acidic vacuoles, and are usually the consequence of the deficiency of an enzyme responsible for the metabolism of vesicular lipids, proteins or carbohydrates. In contrast, mucolipidosis type IV (MLIV), results from the absence of a vesicular Ca ( 2+) release channel called mucolipin 1/transient receptor pot...
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متن کاملCellular sensors of feast and famine.
In response to changes in environmental conditions, animals and humans alike can initiate physiological regulatory mechanisms to assure survival. For example, when food is scarce, the body becomes “thrifty”, and conversely, when it is abundant, physiological “unthrifty” mechanisms are initiated. Recent work has uncovered novel cellular mechanisms of fuel sensing that contribute to these shifts ...
متن کاملWhither the lipid profile: feast, famine, or no free lunch?
A lipid profile (LP) is used in clinical practice to assess risk of cardiovascular disease (CVD) and to guide therapy. The standard LP includes a direct measurement of plasma total cholesterol, triglyceride, and HDL cholesterol concentrations, and derived estimates of LDL cholesterol, non–HDL cholesterol, and lipid ratios (1 ). Expert guidelines recommend that accurate assessment of the LP requ...
متن کاملUndergraduate Physiology Degree Programs in the United States: from Famine to Feast.
The formal teaching of physiology and physiology-related subjects at the undergraduate level in colleges and university in the U.S. is critical for the long-term success of this important area of science. This educational endeavor is a fundamental requirement for the continued movement of students through the “physiology pipeline,” ultimately producing the next generation of physiologists prepa...
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ژورنال
عنوان ژورنال: Oryx
سال: 2016
ISSN: 0030-6053,1365-3008
DOI: 10.1017/s003060531600017x